Pesquisa | Biblioteca Virtual em Saúde

1.

A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.

Harrison, Stephen A; Bedossa, Pierre; Guy, Cynthia D; Schattenberg, Jörn M; Loomba, Rohit; Taub, Rebecca; Labriola, Dominic; Moussa, Sam E; Neff, Guy W; Rinella, Mary E; Anstee, Quentin M; Abdelmalek, Manal F; Younossi, Zobair; Baum, Seth J; Francque, Sven; Charlton, Michael R; Newsome, Philip N; Lanthier, Nicolas; Schiefke, Ingolf; Mangia, Alessandra; Pericàs, Juan M; Patil, Rashmee; Sanyal, Arun J; Noureddin, Mazen; Bansal, Meena B; Alkhouri, Naim; Castera, Laurent; Rudraraju, Madhavi; Ratziu, Vlad.

N Engl J Med ; 390(6): 497-509, 2024 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-38324483

2.

Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH.

Loomba, Rohit; Sanyal, Arun J; Kowdley, Kris V; Bhatt, Deepak L; Alkhouri, Naim; Frias, Juan P; Bedossa, Pierre; Harrison, Stephen A; Lazas, Donald; Barish, Robert; Gottwald, Mildred D; Feng, Shibao; Agollah, Germaine D; Hartsfield, Cynthia L; Mansbach, Hank; Margalit, Maya; Abdelmalek, Manal F.

N Engl J Med ; 389(11): 998-1008, 2023 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-37356033

3.

A randomized, double-blind, placebo-controlled trial of aldafermin in patients with NASH and compensated cirrhosis.

Rinella, Mary E; Lieu, Hsiao D; Kowdley, Kris V; Goodman, Zachary D; Alkhouri, Naim; Lawitz, Eric; Ratziu, Vlad; Abdelmalek, Manal F; Wong, Vincent Wai-Sun; Younes, Ziad H; Sheikh, Aasim M; Brannan, Donald; Freilich, Bradley; Membreno, Fernando; Sinclair, Marie; Melchor-Khan, Liza; Sanyal, Arun J; Ling, Lei; Harrison, Stephen A.

Hepatology ; 79(3): 674-689, 2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-37732990

4.

A global action agenda for turning the tide on fatty liver disease.

Lazarus, Jeffrey V; Mark, Henry E; Allen, Alina M; Arab, Juan Pablo; Carrieri, Patrizia; Noureddin, Mazen; Alazawi, William; Alkhouri, Naim; Alqahtani, Saleh A; Anstee, Quentin M; Arrese, Marco; Bataller, Ramon; Berg, Thomas; Brennan, Paul N; Burra, Patrizia; Castro-Narro, Graciela E; Cortez-Pinto, Helena; Cusi, Kenneth; Dedes, Nikos; Duseja, Ajay; Francque, Sven M; Gastaldelli, Amalia; Hagström, Hannes; Huang, Terry T K; Ivancovsky Wajcman, Dana; Kautz, Achim; Kopka, Christopher J; Krag, Aleksander; Newsome, Philip N; Rinella, Mary E; Romero, Diana; Sarin, Shiv Kumar; Silva, Marcelo; Spearman, C Wendy; Terrault, Norah A; Tsochatzis, Emmanuel A; Valenti, Luca; Villota-Rivas, Marcela; Zelber-Sagi, Shira; Schattenberg, Jörn M; Wong, Vincent Wai-Sun; Younossi, Zobair M.

Hepatology ; 79(2): 502-523, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-37540183

5.

Global survey of stigma among physicians and patients with nonalcoholic fatty liver disease.

Younossi, Zobair M; Alqahtani, Saleh A; Alswat, Khalid; Yilmaz, Yusuf; Keklikkiran, Caglayan; Funuyet-Salas, Jesús; Romero-Gómez, Manuel; Fan, Jian-Gao; Zheng, Ming-Hua; El-Kassas, Mohamed; Castera, Laurent; Liu, Chun-Jen; Wai-Sun Wong, Vincent; Zelber-Sagi, Shira; Allen, Alina M; Lam, Brian; Treeprasertsuk, Sombat; Hameed, Saeed; Takahashi, Hirokazu; Kawaguchi, Takumi; Schattenberg, Jörn M; Duseja, Ajay; Newsome, Phil N; Francque, Sven; Spearman, C Wendy; Castellanos Fernández, Marlen I; Burra, Patrizia; Roberts, Stuart K; Chan, Wah-Kheong; Arrese, Marco; Silva, Marcelo; Rinella, Mary; Singal, Ashwani K; Gordon, Stuart; Fuchs, Michael; Alkhouri, Naim; Cusi, Kenneth; Loomba, Rohit; Ranagan, Jane; Eskridge, Wayne; Kautz, Achim; Ong, Janus P; Kugelmas, Marcelo; Eguchi, Yuichiro; Diago, Moises; Yu, Ming-Lung; Gerber, Lynn; Fornaresio, Lisa; Nader, Fatema; Henry, Linda.

J Hepatol ; 80(3): 419-430, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-37984709

6.

Can Nonalcoholic Steatohepatitis Be Surgically Cured?: Liver Histologic Comparison After Metabolic Surgery Versus Usual Care.

Aminian, Ali; Wilson, Rickesha; Al-Kurd, Abbas; Bena, James; Fayazzadeh, Hana; Alkhouri, Naim; Nissen, Steven E; Dasarathy, Srinivasan.

Ann Surg ; 279(2): 276-282, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-37212393

7.

A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH.

Francque, Sven M; Bedossa, Pierre; Ratziu, Vlad; Anstee, Quentin M; Bugianesi, Elisabetta; Sanyal, Arun J; Loomba, Rohit; Harrison, Stephen A; Balabanska, Rozalina; Mateva, Lyudmila; Lanthier, Nicolas; Alkhouri, Naim; Moreno, Christophe; Schattenberg, Jörn M; Stefanova-Petrova, Diana; Vonghia, Luisa; Rouzier, Régine; Guillaume, Maeva; Hodge, Alexander; Romero-Gómez, Manuel; Huot-Marchand, Philippe; Baudin, Martine; Richard, Marie-Paule; Abitbol, Jean-Louis; Broqua, Pierre; Junien, Jean-Louis; Abdelmalek, Manal F.

N Engl J Med ; 385(17): 1547-1558, 2021 10 21.

Artigo em Inglês | MEDLINE | ID: mdl-34670042

8.

Degree of Discordance Between FIB-4 and Transient Elastography: An Application of Current Guidelines on General Population Cohort.

Chang, Madeleine; Chang, Devon; Kodali, Sudha; Harrison, Stephen A; Ghobrial, Mark; Alkhouri, Naim; Noureddin, Mazen.

Clin Gastroenterol Hepatol ; 2024 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-38428706

9.

Cenicriviroc Lacked Efficacy to Treat Liver Fibrosis in Nonalcoholic Steatohepatitis: AURORA Phase III Randomized Study.

Anstee, Quentin M; Neuschwander-Tetri, Brent A; Wai-Sun Wong, Vincent; Abdelmalek, Manal F; Rodriguez-Araujo, Gerardo; Landgren, Henrik; Park, Grace S; Bedossa, Pierre; Alkhouri, Naim; Tacke, Frank; Sanyal, Arun J.

Clin Gastroenterol Hepatol ; 22(1): 124-134.e1, 2024 01.

Artigo em Inglês | MEDLINE | ID: mdl-37061109

10.

Machine learning models are superior to noninvasive tests in identifying clinically significant stages of NAFLD and NAFLD-related cirrhosis.

Chang, Devon; Truong, Emily; Mena, Edward A; Pacheco, Fabiana; Wong, Micaela; Guindi, Maha; Todo, Tsuyoshi T; Noureddin, Nabil; Ayoub, Walid; Yang, Ju Dong; Kim, Irene K; Kohli, Anita; Alkhouri, Naim; Harrison, Stephen; Noureddin, Mazen.

Hepatology ; 77(2): 546-557, 2023 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-35809234

11.

Safety, pharmacokinetics and pharmacodynamics of obeticholic acid in subjects with fibrosis or cirrhosis from NASH.

Alkhouri, Naim; LaCerte, Carl; Edwards, Jeffrey; Poordad, Fred; Lawitz, Eric; Lee, Lois; Karan, Sharon; Sawhney, Sangeeta; Erickson, Mary; MacConell, Leigh; Zaru, Luna; Chen, Jianfen; Campagna, Jason.

Liver Int ; 44(4): 966-978, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38293761

12.

Cardiovascular disease risk in paediatric and young adult non-alcoholic fatty liver disease.

Simon, Tracey G; Roelstraete, Bjorn; Alkhouri, Naim; Hagström, Hannes; Sundström, Johan; Ludvigsson, Jonas F.

Gut ; 72(3): 573-580, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36522149

13.

Hepatic and renal improvements with FXR agonist vonafexor in individuals with suspected fibrotic NASH.

Ratziu, Vlad; Harrison, Stephen A; Loustaud-Ratti, Véronique; Bureau, Christophe; Lawitz, Eric; Abdelmalek, Manal; Alkhouri, Naim; Francque, Sven; Girma, Hugo; Darteil, Raphaël; Couchoux, Harold; Wolf, Myles; Sanyal, Arun; Vonderscher, Jacky; Scalfaro, Pietro.

J Hepatol ; 78(3): 479-492, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36334688

14.

A global research priority agenda to advance public health responses to fatty liver disease.

Lazarus, Jeffrey V; Mark, Henry E; Allen, Alina M; Arab, Juan Pablo; Carrieri, Patrizia; Noureddin, Mazen; Alazawi, William; Alkhouri, Naim; Alqahtani, Saleh A; Arrese, Marco; Bataller, Ramon; Berg, Thomas; Brennan, Paul N; Burra, Patrizia; Castro-Narro, Graciela E; Cortez-Pinto, Helena; Cusi, Kenneth; Dedes, Nikos; Duseja, Ajay; Francque, Sven M; Hagström, Hannes; Huang, Terry T-K; Wajcman, Dana Ivancovsky; Kautz, Achim; Kopka, Christopher J; Krag, Aleksander; Miller, Veronica; Newsome, Philip N; Rinella, Mary E; Romero, Diana; Sarin, Shiv Kumar; Silva, Marcelo; Spearman, C Wendy; Tsochatzis, Emmanuel A; Valenti, Luca; Villota-Rivas, Marcela; Zelber-Sagi, Shira; Schattenberg, Jörn M; Wong, Vincent Wai-Sun; Younossi, Zobair M.

J Hepatol ; 79(3): 618-634, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37353401

15.

Artificial Intelligence Applications in Hepatology.

Schattenberg, Jörn M; Chalasani, Naga; Alkhouri, Naim.

Clin Gastroenterol Hepatol ; 21(8): 2015-2025, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37088460

16.

MRI-AST (MAST) Score Accurately Predicts Major Adverse Liver Outcome, Hepatocellular Carcinoma, Liver Transplant, and Liver-Related Death.

Truong, Emily; Gornbein, Jeffrey A; Yang, Ju Dong; Noureddin, Nabil; Harrison, Stephen A; Alkhouri, Naim; Noureddin, Mazen.

Clin Gastroenterol Hepatol ; 21(10): 2570-2577.e1, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-36813013

17.

Disease State Transition Probabilities Across the Spectrum of NAFLD: A Systematic Review and Meta-Analysis of Paired Biopsy or Imaging Studies.

Le, Phuc; Payne, Julia Yang; Zhang, Lu; Deshpande, Abhishek; Rothberg, Michael B; Alkhouri, Naim; Herman, William; Hernandez, Adrian V; Schleicher, Mary; Ye, Wen; Dasarathy, Srinivasan.

Clin Gastroenterol Hepatol ; 21(5): 1154-1168, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-35933075

18.

Performance of Noninvasive Tests of Fibrosis Among Asians, Hispanic, and non-Hispanic Whites in the STELLAR Trials.

Wong, Vincent Wai-Sun; Tak, Won Young; Goh, George Boon Bee; Cheng, Pin-Nan; Lawitz, Eric J; Younossi, Zobair M; Vuppalanchi, Raj; Younes, Ziad; Alkhouri, Naim; Wang, Lulu; Liu, Jialuo; Kersey, Kathryn; Myers, Robert P; Harrison, Stephen A; Goodman, Zachary; Trauner, Michael; Romero-Gomez, Manuel; Anstee, Quentin M; Nguyen, Mindie H; Okanoue, Takeshi.

Clin Gastroenterol Hepatol ; 21(1): 90-102.e6, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-35074532

19.

The use of current knowledge and non-invasive testing modalities for predicting at-risk non-alcoholic steatohepatitis and assessing fibrosis.

Kugelmas, Marcelo; Noureddin, Mazen; Gunn, Nadege; Brown, Kimberly; Younossi, Zobair; Abdelmalek, Manal; Alkhouri, Naim.

Liver Int ; 43(5): 964-974, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36864668

20.

MRI-based (MAST) score accurately identifies patients with NASH and significant fibrosis.

Noureddin, Mazen; Truong, Emily; Gornbein, Jeffrey A; Saouaf, Rola; Guindi, Maha; Todo, Tsuyoshi; Noureddin, Nabil; Yang, Ju Dong; Harrison, Stephen A; Alkhouri, Naim.

J Hepatol ; 76(4): 781-787, 2022 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-34798176

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